Paul D. Lampe

Paul Lampe, PhD is a Member and co-Program Head of the Translational Research Program in the Public Health Sciences Division and a Member in the Human BIology Division. He is also a Research Professor in the Department of Global Health and Adjunct Research Professor in DEOHS. The Lampe laboratory investigates the control of cell growth both at the cell biological/ mechanistic level and through cancer biomarker discovery. They study the cell biology connecting gap junctions and intercellular communication (GJIC) with the control of cell growth, the cell cycle and, how the relationship is disrupted during carcinogenesis.

Research Interests

  • The Lampe laboratory investigates the control of cell growth both at the cell biological/ mechanistic level and through cancer biomarker discovery. We study the cell biology connecting gap junctions and intercellular communication with the control of cell growth, the cell cycle and, how the relationship is disrupted during carcinogenesis. Our interest in gap junctions as potential biomarkers of cancer and, more recently, the advent of new screening methodologies has expanded our efforts into broad proteomic screens for potential cancer biomarkers using mass spectrometry and high density recombinant and full length antibody array technologies.

    We are currently collaborating with several Seattle and National and International colleagues to study potential biomarkers for ovarian, colon and breast cancer. These studies involve extensive collaboration between our lab and biostatisticians and epidemiologists. The properties of candidate biomarkers are currently being investigated to determine their role in cancer etiology.
  • Cancer biomarker discovery (both early detection and diagnostic/prognostic) .
    Cell biology and regulation of intercellular communication (GJIC) during wounding and carcinogenesis.

Teaching interests

Cell junctions and disease preventionMentoring Graduate Students and Postdocs
Review date: 
4/30/2017