ECHO PATHWAYS investigators presented recent findings at the national Pediatric Academic Societies Meeting, held in Baltimore, MD, April 24 – May 1, 2019. Dr. Kecia Carroll described an investigation of prenatal phthalate exposure and asthma in the TIDES and CANDLE cohorts. The results primarily showed no adverse effects of phthalates on risk of asthma, though some intriguing differences by child sex were observed. This is one of the largest pediatric cohort studies of phthalates and asthma conducted to date. Dr. Sheela Sathyanarayana presented findings from the TIDES cohort showing that higher levels of maternal hormones during pregnancy are linked to child behavior during preschool. Dr. Alison Paquette was an invited speaker at a symposium, Using Genomics Approaches to Examine the Role of the Placenta in the Developmental Origins of Health and Disease, and described preliminary work on a transcription regulatory network constructed with analyses of placenta from CANDLE and other cohorts.
