January 18, 2021
Environment International published findings from the ECHO PATHWAYS cohort TIDES. Dr. Drew Day was first author and mPI Dr. Sheela Sathyanarayana was last author on the paper, which examined the relationships between everyday ambient exposures to phthalates and adverse child behavioral development. The study includes the measure of several phthalate metabolites across multiple time points during pregnancy across a large sample and a modern statistical approach to analyze mixture exposure associations with outcomes. The results suggest cumulative, additive impacts of phthalate mixtures, with the most important phthalates in that mixture differing by outcome, sex, and timing of exposure.