Hao Wang and Megumi Matsushita present at PANWAT

Matsushita and Wang stand in their lab

Wang (right) won second place for post-doctoral presentation.

On November 9th, trainees Hao Wang and Megumi Matsushita presented at the Pacific Northwest Association of Toxicologists (PANWAT) regional meeting.

Wang won a second-place postdoctoral presentation award for his talk titled "Inducible and conditional stimulation of adult hippocampal neurogenesis rescues mice from Cd-induced hippocampus-dependent memory deficits."  In it he discussed how he used the estrogen receptor modulator tamoxifen to genetically and conditionally stimulate neurogenesis in adult mice, thereby reversing spatial memory and contextual fear memory deficits induced by cadmium exposure. 

Matsushita gave a talk titled "Inducible and conditional activation of adult neurogenesis rescues cadmium-induced hippocampus dependent memory deficits in a mouse model of Alzheimer's disease." She discussed how the stimulation of adult neurogenesis in adult mice expressing an Alzheimer’s disease risk gene, ApoE4, reversed spatial memory deficits induced by cadmium exposure.

PANWAT is the Northwest chapter of the Society of Toxicology, a professional organization dedicated to diversifying the field of toxicology and advancing the benefits of toxicological research for environmental and human health.