UW SRP Research Snapshots

Communicating scientific findings to a variety of appropriate audiences who could benefit from this knowledge was an important component of the UW SRP while it was active from 1986 until the program ended in 2023. To ensure our end-users and other partners have access to information from our interdisciplinary program, we created UW SRP To the Point-Research Snapshots, which are informative lay person handouts about the effects of various neurotoxicants with links to agency resources. Each To the Point-Research Snapshot is a single page downloadable PDF that can be used as informational handouts. You can download and view UW SRP To the Point-Research Snapshots below.

UW SRP To the Point Research Snapshot Handouts:  

Project 1: Biochemical Mechanisms of Olfactory Injury in Salmon 

Dr. Evan Gallagher investigates olfactory system injury in Pacific salmon resulting from exposures to metals, with a primary focus on cadmium to understand how model Superfund neurotoxicants cause neurobehavioral impairment.

Download Project 1 Snapshot Here

Project 2: Cellular and Molecular Mechanisms of Cadmium Neurotoxicity 

Dr. Zhengui Xia investigates mechanisms by which cadmium impairs olfaction and cognition in mice. Her research focuses on the inhibition of normal physiologic signaling in neurons in the brain that are critical for learning and memory.

Download Project 2 Snapshot Here

Project 3: The Role of the Paroxonases (PONs) in Modulating Cadmium and Manganese Neurotoxicity

Dr. Clement Furlong and Dr. Lucio Costa employ animal models and human applications in their ongoing investigation of paroxonase protein levels. They follow both activity and genotype variations that are associated with commonly occurring neurotoxicants such as cadmium and manganese.

Download Project 3 Snapshot Here

Project 4: Arsenic in Shallow Unstratified and Seasonally Stratified Urban Lakes: Mobility, Bioaccumulation and Ecological Toxicity 

The research of Dr. Rebecca Neumann and Dr. Jim Gawel characterizes the biogeochemical factors that control arsenic mobility and bioaccumulation in urban area lakes. The ecological and human health implications of the metalloid contamination remains unclear. The study is providing useful information on the bioavailability of arsenic in nutrient rich conditions.

Download Project 4 Snapshot Here