New assay for PON 1 activity is safer and simpler to use

A new paper by researchers on the University of Washington Superfund Research Program Project 3 describes in detail an improved protocol for characterizing some of the features of Paraoxonase 1 (PON1) that help it provide protection from exposure to certain contaminants and affect susceptibility to disease. Unlike the previously existing protocol, the one reported does not depend on highly toxic substrates and can be carried out in any lab.

Cadmium exposure disrupts the formation of new neurons in a part of the brain responsible for learning and memory

To date, research into the development of Alzheimer's Disease has focused primarily on genetics. Less attention has been given to the role of environmental exposures. However, research from UW SRP Project 2, carried out in the lab of Zhengui Xia, suggested that exposures to contaminants are also relevant, and, surprisingly, that cadmium may play an important role.