Paraoxonase 2 (PON2) could play an important role in reducing the health impacts of toxicants. For this reason, the antioxidant enzyme has interested toxicologists for decades, yet its function in the body still remains mostly mysterious.
A new paper by researchers on the University of Washington Superfund Research Program Project 3 describes in detail an improved protocol for characterizing some of the features of Paraoxonase 1 (PON1) that help it provide protection from exposure to certain contaminants and affect susceptibility to disease. Unlike the previously existing protocol, the one reported does not depend on highly toxic substrates and can be carried out in any lab.
On November 9th, trainees Hao Wang and Megumi Matsushita presented at the Pacific Northwest Association of Toxicologists (PANWAT) regional meeting.
To date, research into the development of Alzheimer's Disease has focused primarily on genetics. Less attention has been given to the role of environmental exposures. However, research from UW SRP Project 2, carried out in the lab of Zhengui Xia, suggested that exposures to contaminants are also relevant, and, surprisingly, that cadmium may play an important role.
Dr. Clement Furlong, a principal investigator on Project 3, Dr.
On April 9th, Megumi Matsushita, a trainee on UW SRP Project Two advised by Dr. Zhengui Xia, was the featured speaker for the monthly meeting of Washington's chapter of the Collaborative on Health and the Environment (CHE-WA).
On April 3rd, 2018 the University of Washington Exposures, Disease, Genomics, and Environment Center a
