Integrative Environmental Health Sciences Facility Core

Catherine Karr, Director
Nicole Errett, Co-Director
Karen Jansen, Manager

Contact Person: Karen Jansen
Phone: 206-685-6392

Bioinformatics & Biostatistics Services:

  • Comprehensive support and analysis of mRNA and microRNA expression array data and miRNA target prediction
  • Comprehensive support and analysis of biological networks and pathways using numerous packages including: weighted correlation network analysis (WGCNA), gene ontology (GO) analysis, Ingenuity Pathway Analysis (IPA), and gene-set enrichment analysis (GSEA).
  • Assistance in the analysis of methylation profiling data derived from targeted enrichment, bisulfite conversion, and massively parallel sequencing
  • Advanced analysis of proteomics data
  • Advanced analysis of metabolomics data
  • Support for integration of different types of OMICs data
  • Facilitate analysis of RNA-seq and ChIP-seq data generated by massively parallel sequencing
  • General statistical consultation & data analysis
  • Support preparation & review of manuscripts, grant proposals

Clinical & Translational Services:

  • Two-way facilitation of interaction between basic scientists and clinical/translational/population-based scientists, to enable innovative approaches that span disciplines.
  • A dedicated core facility space for clinical testing, physiological testing, and collection and storage of human samples.
  • Assistance with IRB issues, identification of staffing solutions for human subjects research, subject recruitment/screening and retention, laboratory assay coordination and organization and application of toxicokinetic approaches.
  • Help developing repositories of samples from well-characterized populations with specific environmental exposures.