Dr. Kissel has a history of research related to human exposure to environmental contaminants. One aspect of this work involves characterization of human dermal contact with soils and sediments. Results of those studies have been incorporated directly into EPA guidance documents, such as the Exposure Factors Handbook, that are used by persons involved in cleanup of Superfund sites or other contaminated lands. Dr. Kissel and his students have also investigated the efficiency of dermal absorption of contaminants from environmental matrices and of skin decontamination by washing. A second research focus area is evaluation of the predictive capability of regulatory exposure models. Particular applications include occupational exposure to pesticides and indoor residential exposure to chemicals found in commercial products. Current activity includes investigation of mitigation of firefighter exposure to carcinogenic PAHs.