My work focuses on neurotoxicology and behavior, primarily using rodent models. I am interested in the molecular and biochemical bases for inter-individual and inter-species differences in susceptibility to environmental chemical exposures, especially with regard to particularly-susceptible populations. I use transgenic and knockout mice and in vitro experiments to investigate these differences in chemical sensitivity. My current work focuses on the neurotoxicity of traffic-related air pollution.
I also manage the Rodent Behavior Core at the UW Center on Human Development and Disability. In this capacity, I have assisted investigators across many different UW departments to carry out, analyze, and publish experiments involving behavioral testing in mice and rats, with a common theme of addressing the cause and treatment of developmental disabilities. I have experience testing rodents in a number of behavioral domains, including learning and memory, anxiety-related behavior, motor functions, sensory functions and reflexes. Areas of interest: Rodent Behavior, Neurotoxicology, Air Pollution, Biochemistry, Environmental Health, Transgenic Mice.