Won-Seok Choi, PhD, MS
Affiliate Professor
Email: choiwcnu@gmail.com
Office: F553, Magnuson Health Sciences Building
Expertise:
Sustainable Communities, Environmental Health, Occupational Health, Risk Assessment
About
Won-Seok Choi, PhD is interested in understanding the mechanisms of neuron death induced in Alzheimer's disease and Parkinson's disease by environmental toxicants. He has investigated signaling pathways triggered by various neurotoxins to define the link to the neuro-degenerative disorders, and to discover therapeutic targets to treat and/or prevent them.
He supports Dr Xia's lab with research, skills training and advice for graduate students.
Education
- PhD, Yonsei University (Seoul)
- MS, Yonsei University (Seoul)
Affiliations
Associate Professor, School of Biological Sciences and Technology
Mentorship
Not available to mentor new PhD and Master's students.
Research
Projects:
- Identification of environmental factors that induces PD.
- Role of mitochondrial complex I and microtubule in neuronal disorders.
- Glial regulation of neuron death in AD and PD.
Publications
Selected publications
- Avenanthramide-C Restores Impaired Plasticity and Cognition in Alzheimer's Disease Model Mice
- Improved memory and reduced anxiety in δ-catenin transgenic mice
- TREM2 promotes Aβ phagocytosis by upregulating C/EBPα-dependent CD36 expression in microglia
- Conditional deletion of Ndufs4 in dopaminergic neurons promotes Parkinson's disease-like non-motor symptoms without loss of dopamine neurons