Marine de Marcken

Title: Background on laboratory animal allergy and recommendations for management of LAA patient care at HAWC

Abstract:

Introduction to Laboratory Animal Allergy

Animal allergens are a significant occupational hazard for laboratory animal workers. Repeated exposures over time may lead to sensitization and laboratory animal allergy (LAA), a form of occupational allergic disease characterized by rhinitis, asthma and/or anaphylaxis. These are hypersensitivity or type 1 reactions of the immune system that result from the production of immunoglobulin E (IgE). Allergies may negatively impact daily life, employment and career opportunities for these workers. The first reported case of LAA occurred in the 1950s, it was discovered to be common starting with cross-sectional epidemiological studies in the 1970s.  Currently, there are no standards for maximum exposure levels to animal allergens in occupational settings in the U.S., and prevention is limited to using personal protective equipment (PPE) and ventilation systems.