Sarah Armel

Project title: Urinary Porphyrin Excretion in Normal and Autistic Children

Degree: MS (Thesis) | Program: Environmental Toxicology (Tox) | Project type: Thesis/Dissertation
Completed in: 2009 | Faculty advisor: James S. Woods


The principal objective of this project was to determine if children with autism have an altered urinary porphyrin excretion pattern compared with that observed in age-matched neurotypical controls. Additional objectives were to establish normative urinary porphyrin concentrations for neurotypical children between ages 2 and 12 years and to confirm or refute reports from other laboratories that children with autism display a unique porphyrin excretion pattern comparable to that previously shown to be associated with occupational mercury exposure in adults.