Dr. Omenn's research focuses on cancer proteomics and informatics. He is especially interested in the role of differential expression of alternative splice isoforms of proteins and transcripts in specific cancer-related pathways. He chairs the Human Proteome Organization (HUPO) global Human Proteome Project (www.thehpp.org). There are datasets for application of analytical tools, and there are research teams eager to engage in collaborative studies in the Chromosome-centric HPP and Biology and Disease-driven HPP initiatives. He has long-standing interests in mechanisms of genetic predispositions to risks from environmental and occupational exposures, pharmacogenetics and pharmacogenomics, and science-based risk analyses.
Dr. Omenn served as Executive Vice President for Medical Affairs and as Chief Executive Officer of the University of Michigan Health System from 1997-2002. He is the director of the UM Center for Computational Medicine and Bioinformatics. He is a past president of the American Association for the Advancement of Science and a member of the Institute of Medicine of the National Academy of Sciences.