Summer

Industrial hygienists use personal samplers to estimate mean breathing zone concentrations of contaminants. The sampling inlet typically is suspended from the worker's lapel. Lapel concentrations are not proven representatives of inhaled concentrations. Researchers have found differences between concentrations at the lapel and at other sites closer to the nose and mouth.

Asthma development in aluminum smelter workers has been attributed to fluoride exposures in the potroom environment. This work focused on the relationship between air and urinary fluoride concentrations to determine if urinary fluoride concentrations could be used as a reliable measure of an individuals dose.

Epidemiological studies have been provided evidence that exposure to electromagnetic fields (EMF) may be associated with an increased incidence of brain tumors, most notably astrocytomas. In this study we investigated whether exposure of human 1321N1 astrocytoma cells to 60Hz EMF would affect their proliferation.

Use of stochastic rather than deterministic estimates of exposure parameters offers the promise of more realistic dose predictions. Separation population variability from uncertainty due to lack of information allows generation of confidence limits on dose distributions and analysis of predictive capability.

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Methylmercury (MeHg) is recognized as a significant environmental hazard, particularly to the development of the nervous system.

Glutathione S-Transferases (GSTs) are a family of broad substrate specificity detoxification enzymes which specialize in the metabolism of reactive substrates with electrophilic functional groups. Even closely related GST isoenzymes can have large differences in activity towards specific substrates.

This study validated a linear regression model describing lead exposure in the demolition industry. A previous lead study (Phase 1) of the demolition industry described lead exposure for many common demolition tasks by use of a multiple regression model. In this study 38 samples were obtained to validate the Phase 1 regression model.

Approaches to assessment of potential exposures to contaminants in the environment are evolving with advances in analytical chemistry, computing power and the methodologies available to researchers.

Introduction: Epidemiologic studies have shown an association between fine particulate matter (PM2.5.) air pollution and mortality, but few large cohort studies have been performed. It is also unclear what populations are at greatest risk.

Workers in the US and around the world face significant risks for dermal exposure to chemicals. In the US in 2003 43,400 skin disease cases were reported to the Bureau of Labor and Statistics for a total incidence rate of 4.9 per 10,000 workers (OSHA 2005) Dermatitis is the second most commonly reported occupational disease in Washington State.

Phospholipid hydroperoxide glutathione peroxidase (GPx4) is a member of the family of selenium dependent enzymes that catalyze the reduction of cell membrane-bound phospholipid hydroperoxides in situ and thus, protects against membrane damage.

Fish consumption advisories are a form of intended risk reduction that aim to warn the public of possible dangers from consuming certain species of finfish and shellfish (herein referred to simply as 'fish'). While developing fetuses and children are particularly susceptible to toxicants in fish, fish also contain valuable nutrients such as Omega-3 fatty acids that promote neurodevelopment.